I gave my 3DS away a while back because it simply didn't feel great in my hands. I experienced hand fatigue while using the 3DS XL as well, so had pretty much given up on portable Nintendo games until the 2DS came out and I decided to give it a shot.
While the plastic in the 2DS doesn't feel high quality, the device has a surprisingly nice weight to it and feels great in my large hands. I never really cared about the 3D functionality in games, so losing that was no big deal. The 2DS does have noticeably better pixel density (but the screens are the same size as a standard 3DS) and games do look a little better on it than a standard 3DS.
Battery life is still simply awful with the device, so that's a letdown, but I didn't expect much. While the design looks like the 2DS is an awkward "doorstop" like many say, it's surprisingly a very comfortable design.
At the end of the day, I'd suggest looking into this cheap option if you don't have a 3DS. I plan to just use it to play SMT games and maybe a little Pokemon.